Public Health
A heavy metal that causes real damage
Every day, several hundred thousand Quebec workers are
exposed to beryllium, a toxic metal that can potentially
cause a pulmonary disease called berylliosis. The symptoms
of this disease include a shortness of breath, coughing,
chest pain and general weakness.
Between 1999 and 2002, 16 workers were recognized as suffering
from chronic berylliosis by a committee set up by the Occupational
Health and Safety Commission (CSST). Another 33 workers are
probably affected to a lesser degree, 12 of these being recognized
as having sub-clinical berylliosis and another 21 as sensitized
to beryllium. Their average age is 46 years.
“Some cannot work anymore and their quality of life
is diminished,” explains Joseph Zayed of Université de
Montréal. “Although the disease cannot be cured,
the symptoms can be treated by medication. While the disease
is well known to occupational health specialists, and the
first emission standards date back to 1949, the precise mechanism
by which it attacks the respiratory tract is still unknown.
However, a research project under the direction of Professor
Zayed seeks to shed light on the microscopic dust that appears
to cause the disease. The Robert Sauvé Occupational
Health and Safety Research Institute (IRSST) will provide
close to one million dollars in funding for the research.
Workers in industries that use beryllium are most at risk:
non-ferrous foundries, aluminum smelters, welding and semi-conductor
ceramics manufacturing plants, manufacturers of aeronautic
parts, arms, and nuclear energy industries. The most insidious
thing about its effect on the respiratory tract is that the
period of exposure to the metal can be relatively short,
while the symptoms appear many years later. “The symptom
latency period, which means the time between the first exposure
and the appearance of signs of the disease, is generally
from 10 to 15 years. The disease may appear while the subject
is still being exposed to beryllium, or it may not appear
until 25 years after the last exposure,” according
to a document put out by the Ministry of Labour.
“We are going to use animal models to test three
chemical forms of beryllium, pure beryllium, beryllium oxide
and beryllium copper. Our working hypothesis is that toxicity
varies from one form to another,” explains the professor,
who is connected to the Department of Environmental and Occupational
Health in the Faculty of Medicine.
The implications of this research could be far-reaching,
as international standards could be revised depending on
the toxicity of the different chemical forms of the metal. “Currently,” explains
Mr. Zayed, “the scientific community believes that
there is not enough toxicological information and scientific
knowledge on workers’ exposure to firmly establish
a new standard of occupational exposure.”
Researcher: |
Joseph Zayed |
Email: |
joseph.zayed@umontreal.ca |
Telephone: |
(514) 343-5912 |
Funding: |
Institut de recherche
en santé et sécurité au travail |
|